INNOVATIVE THERAPIES BASED ON A NEXT-GENERATION DRUG DELIVERY PLATFORM

Core Technology

At MDimune, we are passionate about changing the world by developing innovative therapeutics.

  • Large-scale production of
    therapeutic vesicles
    from cells
    using direct extrusion method

    Exosomes are nanosized vesicles naturally released from various types of cells, including immune cells and stem cells. Exosomes have garnered broad attention as a next-generation drug delivery system with their roles in various intercellular communications. However, a minuscule quantity of exosomes has been a drawback for commercialization.

    MDimune Inc. developed the BioDrone® Technology for producing cell-derived vesicles (CDVs, exosome mimetics) in a large quantity from various cell sources by extrusion method. MDimune Inc. is currently optimizing this innovative platform technology to tackle various human diseases.

  • Targeted drug delivery platform
    that minimizes side effects and
    maximizes efficacy

    As drone delivery will likely transform courier services by providing speedy and accurate package delivery, the human cell-derived vesicle(CDV)-based drug delivery platform, BioDrone® Technology, will enable highly targeted drug delivery to specific lesions by utilizing immune cell- and stem cell-derived vesicles loaded with drugs. The innovative target-specific delivery by BioDrone® Technology will minimize side effects and maximize the efficacy of drugs by using minimal doses.

  • Stem cell-derived vesicles as
    innovative therapeutics for
    treating incurable diseases

    By combining the regenerative potential of stem cells with proven efficacies of various drugs loaded in the vesicles, these novel therapeutics based on stem cell-derived vesicles will provide synergistic effects for treating incurable diseases.

  • BioDrone® Technology utilizes
    cells from diverse human
    tissues and transformed cells

    Versatility is one of the compelling advantages of our direct extrusion technology. By utilizing various types of human cells from different organs as well as cells transformed to harbor specific traits, we can produce vesicles delivering drugs to desired targets. MDimune Inc. is currently collaborating with pharmaceutical companies who are interested in applications of the BioDrone® Technology in various unmet medical needs.

  • Cell-Derived Vesicles (CDVs)
    vs Exosomes

    CDVs are a next-generation drug development platform technology. CDVs are similar to exosomes in size, properties, and functions but exhibit substantial advantages through large-scale production and versatility of using various cell types.

Patents

NO Patent name Application/
Registration
Application/Registration
Number
Country Registration
Date
17 분산성이 우수한 세포 압출장치 및 이를 이용한 세포 압출 방법
(CELL EXTRUDING APPARATUS WITH EXCELLENT DISPERSIBILITY ...
등록
Registration
10-2154135 한국
KR
2020.09.03
16 세포 유래 베시클 제조 방법 및 이의 활용
(Cell-derived vesicle manufacturing method and use thereof)
출원
Application
10-2020-0065172 한국
KR
-
15 단백질 항상성 조절인자가 풍부한 세포 유래 베시클 및 이의 제조 방법
(Protein homeostasis regulator enriched cell derived ...
출원
Application
10-2020-0061867 한국
KR
-
14 세포 유래 베시클의 정제 방법
(Purification method of cell derived vesicle)
출원
Application
10-2020-0051513 한국
KR
-
13 프로테오믹스를 기반으로 한 세포 별 마커 조성물
(Cell-specific marker composition based on proteomics)
출원
Application
10-2020-0045396 한국
KR
-
12 멤브레인 모듈을 포함하는 세포 압출장치 및 이를 이용한 세포 압출방법
(CELL EXTRUDING APPARATUS COMPRISING MEMBRANE MODULE ...
등록
Registration
10-2134906 한국
KR
2020.07.10
11 표적 단백질을 포함하는 세포 유래 베시클 및 이의 제조방법
(Cell-derived vesicle comprising the target protein and...
출원
Application
10-2020-0005014 한국
KR
-
10 세포 유래 베시클을 이용한 침샘 질환 예방 또는 치료용 조성물
(Composition for preventing or treating salivary gland ...
출원
Application
10-2019-0110816 한국
KR
-
9 세포 압출기 및 세포 압출방법
(Cell extruder and Cell extrusion method)
등록
Registration
10-2142479 한국
KR
2020.08.03
8 표적 단백질을 포함하는 세포 유래 베시클 및 이의 제조방법
(Cell-derived vesicle comprising the target protein and ...
출원
Application
10-2020-0005014 한국
KR
-
7 간엽줄기세포 유래 인공나노좀을 포함하는 폐질환 예방 또는 치료용 약학적 조성물
(MICROVESICLES DERIVED FROM NUCLEATED, MAMMALIAN ...
출원
Application
16/205,277 미국
US
-
6 간엽줄기세포 유래 인공나노좀을 포함하는 폐질환 예방 또는 치료용 약학적 조성물
(MICROVESICLES DERIVED FROM NUCLEATED, MAMMALIAN ...
등록
Registration
10-2035716 한국
KR
2019.10.17
5 포유류의 유핵세포에서 유래된 마이크로베시클 및 이의 용도
(MICROVESICLES DERIVED FROM NUCLEATED, MAMMALIAN CELLS AND ...
등록
Registration
2450032 유럽
EP
2018.09.05
4 포유류의 유핵세포에서 유래된 마이크로베시클 및 이의 용도
(MICROVESICLES DERIVED FROM NUCLEATED, MAMMALIAN CELLS AND ...
등록
Registration
ZL201080037538.X 중국
CN
2014.05.28
3 포유류의 유핵세포에서 유래된 마이크로베시클 및 이의 용도
(MICROVESICLES DERIVED FROM NUCLEATED, MAMMALIAN CELLS AND ...
등록
Registration
5667180 일본
JP
2014.12.19
2 포유류의 유핵세포에서 유래된 마이크로베시클 및 이의 용도
(MICROVESICLES DERIVED FROM NUCLEATED, MAMMALIAN CELLS AND ...
등록
Registration
US 10,675,244 B2 미국
US
2020.06.09
1 포유류의 유핵세포에서 유래된 마이크로베시클 및 이의 용도
(MICROVESICLES DERIVED FROM NUCLEATED, MAMMALIAN CELLS AND ...
등록
Registration
10-1314868 한국
KR
2013.09.27